Your system is slow because you are loading too much at startup- all of those entries will run in the backgrouns. Eventually, they will slow you down. Combofix remove some inappropriate entries and the second HJ log looks better than the first.
My first concern is the large number of 016 entries you have in The HijackThis log. Most are for games. These are Active X Objects- add-ons-and the fewer you have the better. I suggest you disable as many as you can:
Open Internet Explorer> Tools> Manage Add-ons>> there are 2 sections> 1. Add-ons currently running and 2. Ad-ons previously running. Check bith sections by clicking on the small arrow point to the right of the dialog box. To disable, highlight first> disable> Apply> OK when finished.
You have 24 of these running.
I see you are running the Viewpoint Manager.
Viewpoint is considered foistware and is not needed on your computer.I strongly suggest you remove it:
Download and unzip the ViewpointKiller to own folder on Desktop
HERE
Run ViewpointKiller.exe
Reboot.
ViewpointKiller 1.2 FinalViewpointKiller does exactly what it's name says: Kills Viewpoint Media Player. Viewpoint Media Player is an adware that displays bandwith eating popup ads in IE and on your desktop. It comes silently with an install of AIM and will be reinstalled by AIM if uninstalled.ViewpointKiller fixes all of that. It takes off Viewpoint Media Player once and for all.
(Thank you, touch)
Please open HijackThis, and select
Do a system scan only.
Place a checkmark next to the following entries (if present):
1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = *.local
O2 - BHO: (no name) - {02478D38-C3F9-4efb-9B51-7695ECA05670} - (no file)
Then, close all other open windows, leaving only HijackThis open, and select
Fix checked.
Please run a full system scan with your AV program and if anything is found, attack the log.
Please tell me what system problems you are now having.