My homebuilt PC has the most aggravating problem that I hope someone can help me with. It has an ASUS A7N8X Deluxe motherboard with an AMD Athlon XP2500+ processor running WIN98SE. It has 512megs of DDR memory and a Verto GeForce FX graphics card. It's mounted in an Antar case with a 300w power supply. The problem is that with no warning what-so-ever it will fail to boot into Windows, after about two weeks of working fine daily. The problem has happened 5 times since I first put it together in February and the only way I've ever been able to get it running again is to FDISK, reformat the drive and start all over again, loading all the software again from scratch. This is getting old. It will run fine for about two weeks then the next time I go to start it up ...nothing but a blank screen with a blinking cursor. It will run in SAFE mode. If I do the step-by-step start-up it always fails at loading the msmouse.vxd file. I also tried reloading Windows but when it gets to the point where it’s ready to restart, it hangs again. I've tried all the MS Knowledge base ideas and nothing worked. The virus software is up to date. HD diagnostics fail to find anything wrong. I’m getting pretty exasperated, so before I go through the whole scenario again, I’d sure like some help figuring out what could be wrong. Can anybody help? Thanks. 12/02/04 Since I posted that message to a PC Enthusiast Board back in May, I upgraded the power supply to a 650 watt unit and have started all over with different HDs, but it still fails the EXACT SAME WAY. It has run several times for longer than two weeks and in fact this last time it ran for more than 3 months, then just like every time before, I went to start it up and it's gone again. Monitoring the temperature with the ASUS Probe feature says everything is OK but lately I've been thinking that maybe my BIOS is defective or I have a bad version mobo. Any other thoughts would be most welcome. Thanks very much, Mark K.