precisely what software are you using to import photos? Software will usually save defaults like this in either the registry or a configuration file in the directory from which the software runs.
As an example, if you run regedit32 and do a 'find' for one of your more obscure (i.e. non-standard) destinations, you may certainly turn up one or more places in the registry referring to it. Note the destination may be in 'long' format or 'dos' format. Test both formats in your search. For example you might search for c:\mypics\lovely holidays, and the dos version of that might be c:\mypics\lovely~1.
If these destinations are in the registry, then right next to them will be all the others, and you can simply delete what you don't want.
If the destinations are not in the registry, and you are using a non-MS package, then uninstalling that package plus deleting the original directory it was installed in (if necessary) will put you back to square one and you can re-save a few things to your required destinations only.
