Okay, this just started happening a few minutes ago, I was in Photoshop and all of a sudden I wasn't able to left click any of my windows. I figured my computer had just frozen or something so I restarted. No luck, and AdAware started alerting me to a bunch of registry edits which I of course blocked. Now I still can't left click anything and all my shortcuts turned into default .lnk files. I'm still able to actually open programs and run them by using tab, space bar, and the arrow keys to navigate windows. I'm not sure what's going on, AVG, Spyboy Search and Destroy, Lavasoft Adaware, and Registry Mechanic aren't finding any issues.