need to supply more details here. What exactly do you mean? it wont hold an OC? or the sliders are not active? It looks like you can move the HT ref at least.
....and first off, I see you moved the PCIE reference clock to 110Mhz...bad idea. keep it at 100mhz. it does not add any performance to speak of, and most systems will artifact if not crash at anything over 105mhz. I bet when you hit "apply' with the PCIE moved...it just sits there and "thinks" forever...right?
If this was at 110 when you installed AOD, go into your BIOS and set the PCIE to 100mhz.