Ctrl Alt Del not working + computer very very slow

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Today my computer has died a thousand deaths.

I have done a Panda Virus scan and it found a worm which it destroyed, now I find myself with a slow computer with CTRL ALT DEL not functioning and also unable to access e-mails in my hotmail acocunt even though they are showing as available.

Programs are taking in excess of 60 seconds to open. An eternity in today's expectations.

Also just run HIJACK THIS which has logged the following:

Logfile of HijackThis v1.99.1
Scan saved at 17:04:12, on 23/09/2005
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP2 (6.00.2900.2180)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\csrss.exe
C:\WINDOWS\SYSTEM32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\Program Files\Panda Software\Panda Titanium 2006 Antivirus + Antispyware\TPSrv.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\Panda Software\Panda Titanium 2006 Antivirus + Antispyware\PavFnSvr.exe
C:\Program Files\Common Files\Panda Software\PavShld\pavprsrv.exe
C:\Program Files\Panda Software\Panda Titanium 2006 Antivirus + Antispyware\pavsrv51.exe
C:\Program Files\Panda Software\Panda Titanium 2006 Antivirus + Antispyware\FIREWALL\PNMSRV.EXE
C:\Program Files\Panda Software\Panda Titanium 2006 Antivirus + Antispyware\PsImSvc.exe
C:\WINDOWS\System32\wdfmgr.exe
C:\WINDOWS\System32\alg.exe
C:\WINDOWS\system32\wscntfy.exe
C:\WINDOWS\Explorer.EXE
C:\Program Files\Panda Software\Panda Titanium 2006 Antivirus + Antispyware\APVXDWIN.EXE
C:\WINDOWS\system32\ctfmon.exe
C:\Program Files\Panda Software\Panda Titanium 2006 Antivirus + Antispyware\WebProxy.exe
C:\Program Files\Internet Explorer\IEXPLORE.EXE
C:\Documents and Settings\Owner\Desktop\HijackThis.exe

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Bar =
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.google.co.uk/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Bar =
R1 - HKCU\Software\Microsoft\Internet Explorer\Search,SearchAssistant =
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant = about:blank
R1 - HKCU\Software\Microsoft\Internet Explorer\SearchURL,(Default) = about:blank
R1 - HKLM\Software\Microsoft\Internet Explorer\SearchURL,(Default) = about:blank
R3 - Default URLSearchHook is missing
F2 - REG:system.ini: UserInit=C:\WINDOWS\system32\Userinit.exe
O2 - BHO: AcroIEHlprObj Class - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 5.0\Reader\ActiveX\AcroIEHelper.ocx
O2 - BHO: (no name) - {0E77F6D7-29CB-3118-540F-D65A6896698C} - C:\WINDOWS\system32\FYI\srihiqijke.dll (file missing)
O2 - BHO: (no name) - {53707962-6F74-2D53-2644-206D7942484F} - C:\Program Files\Spybot - Search & Destroy\SDHelper.dll
O2 - BHO: (no name) - {5C8B2A36-3DB1-42A4-A3CB-D426709BBFEB} - (no file)
O4 - HKLM\..\Run: [UserFaultCheck] %systemroot%\system32\dumprep 0 -u
O4 - HKLM\..\Run: [winupdates] C:\Program Files\winupdates\winupdates.exe /auto
O4 - HKLM\..\Run: [APVXDWIN] "C:\Program Files\Panda Software\Panda Titanium 2006 Antivirus + Antispyware\APVXDWIN.EXE" /s
O4 - HKCU\..\Run: [CTFMON.EXE] C:\WINDOWS\system32\ctfmon.exe
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~1\OFFICE11\EXCEL.EXE/3000
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\j2re1.4.2\bin\npjpi142.dll
O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\j2re1.4.2\bin\npjpi142.dll
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MICROS~1\OFFICE11\REFIEBAR.DLL
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O12 - Plugin for .spop: C:\Program Files\Internet Explorer\Plugins\NPDocBox.dll
O16 - DPF: {4C39376E-FA9D-4349-BACC-D305C1750EF3} (EPUImageControl Class) - http://tools.ebayimg.com/eps/wl/activex/EPUWALControl_v1-0-3-24.cab
O16 - DPF: {4F1E5B1A-2A80-42CA-8532-2D05CB959537} (MSN Photo Upload Tool) - http://by101fd.bay101.hotmail.msn.com/resources/MsnPUpld.cab
O16 - DPF: {6414512B-B978-451D-A0D8-FCFDF33E833C} (WUWebControl Class) - http://v5.windowsupdate.microsoft.c...ls/en/x86/client/wuweb_site.cab?1110302954015
O16 - DPF: {917623D1-D8E5-11D2-BE8B-00104B06BDE3} (CamImage Class) - http://195.224.159.71/activex/AxisCamControl.cab
O16 - DPF: {B38870E4-7ECB-40DA-8C6A-595F0A5519FF} (MsnMessengerSetupDownloadControl Class) - http://messenger.msn.com/download/MsnMessengerSetupDownloader.cab
O20 - Winlogon Notify: avldr - C:\WINDOWS\SYSTEM32\avldr.dll
O23 - Service: Panda Function Service (PAVFNSVR) - Panda Software - C:\Program Files\Panda Software\Panda Titanium 2006 Antivirus + Antispyware\PavFnSvr.exe
O23 - Service: Panda Process Protection Service (PavPrSrv) - Panda Software - C:\Program Files\Common Files\Panda Software\PavShld\pavprsrv.exe
O23 - Service: Panda anti-virus service (PAVSRV) - Panda Software - C:\Program Files\Panda Software\Panda Titanium 2006 Antivirus + Antispyware\pavsrv51.exe
O23 - Service: Panda Network Manager (PNMSRV) - Panda Software - C:\Program Files\Panda Software\Panda Titanium 2006 Antivirus + Antispyware\FIREWALL\PNMSRV.EXE
O23 - Service: Panda IManager Service (PSIMSVC) - Panda Software Internacional - C:\Program Files\Panda Software\Panda Titanium 2006 Antivirus + Antispyware\PsImSvc.exe
O23 - Service: Panda TPSrv (TPSrv) - Panda Software - C:\Program Files\Panda Software\Panda Titanium 2006 Antivirus + Antispyware\TPSrv.exe


Any ideas?
:giddy:
 
Have you also checked for spyware if not, run updated scans ( Adaware and SPybot S&D are great utilities) its possible ur system may be still infected.Clean out the junk by running disk cleanup, this will free up some space too, if ur low on it (maybe CCleaner wud be a gud option) and then run chkdsk and defragment as its also possible ur drive is cluttered, and causing the slowdown.
 
Thanks guys,

I took advice and in the end did the following:

Run Anti-Virus again, used CleanUp40, then chkdsk, defrag. It still ran very slow until I removed the Panda anti-virus, I have heard of issues with the OS when using Panda before but not to this extent.

All is now good and I have installed AVG anti-virus and no speed issues.

Seems Panda was swallowing all of the performance and on a machine running a P4 that is very BADDD!
 
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