I have never encountered this issue and have no idea what to do or think. I have an ASUS DirectCU II R9 280X card. I have it installed in a Gateway DX 4380 motherboard with A10-5700 and 8GB 1600 RAM. Everything is powered by a 725Watt cooler master PSU. Everything has been running well until a couple of days ago. Then I noticed the video wouldn't wake up from sleep. I've had that problem across many computers, before, so I wasn't all too worried. Then my PSU died. I had a thermaltake TR2 600 watt then. So I exchanged it as I only bought it the of day before. The other worked fine, but I started getting freezes. Usually after I put a strain on the video card, like gaming for an hour or so. I'd finish the game and return to desktop and everything would freeze. I thought that maybe the power supply was faulty, again. So I went and returned it and got the CM one. But the problem is still the same. I'd play for a while, exit and as soon as I reach the desktop everything freezes. I know that it is possible that it's the video card that is faulty, But I am also thinking that maybe (fingers crossed) that the mobo I got is just unable to handle this card. Maybe it's just unable to deliver enough power through PCI-E that this card needs. I have a spare HD7850 that works just fine, but it's not really the same power draw as r9 280x so I don't think the results would be a proof of anything. Another thing I did notice is that when I had 7850 installed and played Guild Wars 2 I had no problem maintaining 60FPS, but with this card, on the same settings I dropp to mid 20s in many places. Anyway. What is the most likely cause? Video card or just a crap of a mobo (considering it's from a pre-built PC)? Sorry the pics are a bit fuzzy. I have very shaky hands and this is the best I could do.