Partially taken from http://www.computerandvideogames.com/article.php?id=257338 Common knowledge to hardcore gamers, but good info for the rest. Edit Works for Radeon and Nvidia. Nvidia "Open the Control Panel, choose 'Manage 3D setting' and 'Antialiasing - Mode'. Now tick off 'Override any application setting' and force your favorite Anti Aliasing level in 'Antialiasing - Setting'. Radeon Navigate through Catalyst Control Center in a similar fashion.