I've changed mobos and used the same install (not even repaired) several times that worked, and several times it didn't. It's hit or miss. Going ASRock dualSATA2 to DFI UltraD had no problems. Going from My Tforce6100-939 to a ECS P4M800 M2 was also problem free after a re-activation (I didn't even have to call.) I could not get 865P to VIA to work, or going from VIA to 965P eather. If it wont just work I usually just start over with a clean install, that's for the best anyway.