Task Manager and Regedit don't work

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When i use ctrl+alt+del, nothing happens. Selecting the task manager from the taskbar doesn't work either. Starting taskmgr from run gives me the error message: "Another program is currently using this file."
When i try to open regedit from Run, it appears for a second, then this pops up:

C:\Windows\system32\regedit.com
The NTVDM CPU has encountered an illegal instruction.
CS:054d IP:0102 OP:ff ff 83 3e 51 Choose 'Close' to terminate the application.
 
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