Hello and welcome to Techspot.
Run HJT with no other programmes open. Have HJT fix the following, by placing a tick in the little box next to(if there).
Fix all 016-DPF entries.
O18 - Protocol: msnim - {828030A1-22C1-4009-854F-8E305202313F} - "C:\PROGRA~1\MSNMES~1\msgrapp.dll" (file missing)
Click on the fix checked button.
Close HJT.
Reboot your computer and let us know if you can access task manager.
Post a fresh HJT log.
Regards Howard :wave: :wave: