Usb flash drive problems

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I am having some problems with my flash drive. It works fine in all other computer but, if I plug it in my downstairs computer it says Z:\ is not accessible Access is denied. When I try to format it the thing gives me a : You do not have sufficient rights to perform this operation. Whats wrong? If it helps I have other usb devices that work but all flash drive don't work. Also I just did a registry clean-up using Ccleaner but I backed up the changes to the registry and when I noticed somthing was wrong I loaded the back-up. That did'nt help at all.
 
There isn't a security settings tab. If there is I must not be doing this right please explain in detail. The right-click also shows that is is an unknown file system.
 
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