In no particular order : PvPonline Penny Arcade Dork Tower CTRL+ALT+DEL Little Gamers Ornery Boy Ink Tank ( Home of Angst Technology ) *Currently in hiatus* Red Meat *Courtesy of StormBringer* User Friendly VG Cats Wizard of Cheese Nodwick FoxTrot I'll add a few more, as I couldn't post all of them right now but feel free to contribute.
Penny Arcade is the only thing I read out of those - and only rarely. Does Strongbad count as a comic?
Beetle Bailey is one of my favorites. Also ucomics.com Oh, almost forgot my hero Andy Capp, also at ucomics.
I just read 2 series regularly... UserFriendly (as Didou) and RealLife Comics... The latter is a quasi-blog-scifi series, which has it's moments, but a lot of it passes me by since I don't live in the US...
Elftor (dont go read elftor if you have a problem with bad language or are offended easily), user friendly, and sometimes JTHM.
Homestar! I can believe no one has mentioned Homestar! Oops. someone did. But at least I added a link. If you haven't seen it, you owe it to yourself to check it out.
I read Dilbert occationally - it kind of makes fun of a corporate environment and management, which is a lot of the crap I hear about in classes. A bit off from comics but I do watch all the stongbad e-mails and also the red vs blue cartoons.
Yeah.. old topic, I know, but I have a new favorite now Nemi Unfortunately looks like MrGaribaldi and me are the only ones who understand this (well, he understands the language, maybe not humor). Maybe Per Hansson too.