First, willkommen to this PERFECT forum (don't worry, i'm not a mod
)
Second, regarding your question, it depends. In other words, NTFS, i guess, doesn't have anything related to PCs specs, nor does FAT.
But there're differencies and benefits in using NTFS.
In NTFS, you can have a partition size > 32 GBs (as far as i remember) and its max. size is limited by your HDD itself
, whereas in FAT32, partition size can't exceed this 32 gigs. You can have a file size more than 4 GBs, but in FAT32, the maximum size for ONE FILE is 4 GBs and you can't exceed it.
In NTFS, you have some files' security by their encryption and also you have a built-in compression for your files if you like.
My opinion: Make some partitions FAT32 and few NTFS or only one if you like, because you don't need to make them all NTFS and in case you install another OS, (older one SPECIFICALLY) NTFS might not be readable, whereas FAT32 is readable...