HijackThis Logfile...computer is exploding

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Two days ago I let a friend use my computer as I slept...and I woke up the next morning to find it full of BS. I worked hard to keep it spick and span, and now it's suffocating! I've run AdAware and SpyBot numerous times, and tried to analyse the HijackThis log...some things I wasn't able to delete, even in safe mode. I also have tried to run regedit...it tells me it is not a valid Win32 application! Help!

(I've yelled at my friend nonstop for the past couple days)
 
All right, thanks for all the help! I noticed the surfsidekick thing right away, but nothing I did would make it go away...it still said it was running when I tried to delete it in safemode. Thanks again : D
 
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