HijackThis scan help

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Hi, I am new.... We just bought a laptop from my sister. It has vista home premium. I am getting the trojan.zlob-X.a popup I read the directions to run the hijack scan but when it goes to save the log in notepad it just comes up blank and there is nothing to see. I am just wondering what I am doing wrong so I can take care of this problem. Thanks.
 
Hi,

Try reinstalling HijackThis and renaming it again on your system. You may download it from my signature.
 
I did and it still won't work. I have vista on this. the note pad pops up ask if I want to create the file. I click yes and it gives me a blank doc, if I click no it closes.
 
Try running a ComboFix scan then. Complete as much of the steps in preliminary removal thread sticky in this forum and attach the required logs.
 
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