Sony's Vaio U series is one of the smallest “laptops” around, almost resembling a PDA due to its small profile. Weighing in at just a tad over a pound, it has many features a PC offers and is designed completely around people who want high mobility and high functionality.
There is a very limited selection of large flash storage available for use in the desktop and mobile sector, but companies that pioneer offerings like this will get people interested in it more. Once the advantages are seen to outweigh the extra cost and sacrifice in disk space, we will probably see a lot more manufacturers following suit. I've long been waiting for the day when I could shop for a 60GB flash drive that uses a fraction of the power of a typical desktop hard drive, and that day now seems to be approaching faster than ever.