I have the exact same problem -- cannot get into bios by F2 key, F12 key, ESC key, or any other key combinations. Eventually I found out that it is because the current Bios is set as 'Quick Boot' and boot order is set to 'HDD/SSD'. In this mode, at power up, Bios boots straight to Windows on HDD without showing F2 or F12 prompt. The result is you cannot access Bios. The only way to change it is to use the HWSetup utility provided by Toshiba (download and install it). Then, you run it and select 'Biso' menu to change the 'quick boot' to 'Normal'. That it is. Next time, you will see the happy F2 prompt at boot up.