I saw a similar post and ran the recommended tools, smitfraud, virtumundo, vindofix, look2me, as well as trojan hunter, adaware, spybot, AVG and a slew of others. They always find things to clean and they always come back. Mostly I get win???.tmp.exe and Pakes.U and Generic.WUE I also get Isnotify, Issearch etc. They are getting more and more aggressive. After trying to run virtumundo my system crashed and I could no longer start in Safe Mode. Please help, and thanks in advance!