My last encounter on vista was "windows defender virus." It told me a bunch of programs were infected even an iTunes program (Bonjour). So I did a system restore. That fixed it. McAffee was slowing down my system so I tried Linux. Now I've been using Ubuntu 10.04LTS for quite some time now and my laptop now works even better. No more anti-virus! Plus I made a bootable DVD from it and use it on other pc's.

And this is why I gave McAfee the flick: they originally screwed up my system so bad during install that it would always boot-up to a BSoD.

Luckily Trend Micro has been given me good times ever since…

People who actually know a thing or two about antivirus protection stay the hell away from norton. but norton works just fine as long as you don't do stupid thing on the internet.. as for me i use MSE (the best free antivirus for win7, but i don't recommend it for XP) and kaspersky (best paid one - alongside bitdefender) when i need the extra protection.
Let's not forget that common sense is the best protection you can have.