Is it possible to run Oracle on a regular PC?

Is it possible to run Oracle on a regular PC? My teammates use AI medical robot with SQL. see: http://www.rdoctor.com But it is slow. They think to change to Oracle. However, no experince. Does anybody know if it is easy to change to ORacle and can oracle be used on a regular PC or on cheap server (up to coupel thousandds), or can it work with big mahcine only? any comments?

windows 2000 or xp pro or the server editions
1gb memory and about 10gb of space to start
need the disc's fo version 8 I got a box full
very steep learning curve,but highly stable DB and gui system
goes past the ms data base of 4gb