I use O&O Defrag weekly to defrag my hard drive and Uniblue's Registry Booster to clean and defrag my registry files also... Ive recently been surfing and Ive read a lot of comments about how I shouldnt use registry cleaners. I was wondering if I should drop the Registry Booster application or only use it for the defrag option.

Use only the Registry "cleaners" that you have the knowledge to understand. Do not give some fancy schmancy registry program a chance to really screw-up things. If you do NOT understand exactly what your Registry Editor is doing, you have encumbered too much risk.

Okay thanx, Registry Booster is really easy and I think anyone would understand it. Another question... should I continue using its registry defrag function as well???

you don't get much out of that
reg does not get very fraged unless your writing to it alot
the old saying if it works why fix it
your better off defragging paging file once a month

I use CCleaner. It's a great program that has a lot of other features.