ASUS mobos are picky about RAM; certain RAM, such as OCZ kits, cause BSODs and the like. They only tend to accept Corsair, Crucial, and certain G.SKILL kits without any trouble. Also, sometimes the arrangement of NB heatsinks and other components on ASUS boards is odd, which sometimes leads to clearance issues if you want to install a large CPU HSF or other kinds of coolers.
Gigabyte mobos are, for the most part, free of such issues. They also generally have a larger selection of motherboards to choose from, at various price points.