High pitched noise coming from comp and no use of monitor, keyboard, or mouse

I recently got my net back on. I did all suggested driver updates. After installing a game and turning off the comp, when I went to turn it on all I got was a high pitched noise from inside the comp along with no use of my monitor mouse or keyboard. I took the video cards out cleaned them and put them back in, Comp ran fine till I put the game back on the comp. I am now in the same position of high pitched noise along with no keyboard, mouse or monitor.
I have a
Dell 630i quad core
GeForce 8800GT x 2
OS- Windows XP

I have removed each of the video cards and tried running the comp, but still not working same high pitched noise.

Please help!! I want my comp back in working order
 
"Comp ran fine till I put the game back on the comp. "

?

Personally, I would call Dell on this one. Who knows, maybe you're still under warranty and you'll get a free motherboard replacement. :D
 
it's a high pitched noise. One long beep.
and the mobo was replaced a year ago :/

the fans start on the comp and video cards that is it.
 
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