I've seen some other threads with problems similar to mine, but with some distinguishable differences. I greatly appreciate any help anyone can offer on my problem: First some basic info on my system: - Windows Vista 32 bit, have latest service pack - Toshiba Satellite When I plug in any USB mass storage device (i.e. thumb drives, my JVC digital camcorder), my computer recognizes that they are there, but I cannot open them. To be more specific: I plug in my JVC, I hear the notification, and my file copying software for the camera launches. However, when I try to access the drives (it takes two, (F & (G, it cannot access them. Furthermore, when I click on the backup option it says that no device is plugged in. When I plug in my thumb drive, I hear the notification, but then the autolaunch doesn't happen. I then go to my computer and click on the drive (E, and windows says that the drive has to be formatted before it can be used... never had that happen before. Any how, I finally tried formatting one of my thumb drives and it couldn't successfully format it either. I have no idea why this is happening, but I do know when it started... I have a Sandisk Cruizer. It has always run fine on my computer, but I had it set-up to run as a storage device only (i.e. without the programs option). However, one day I decided to try and pull some files from another computer which it had never been used on. So I plug it in and it ends up installing the Sandisk software on it with the drive partitions and protections for running programs and all that jazz. I then decided to go back and change the settings on the drive to remove that and just make it a storage device for that computer. So it works and I can read it fine on the other computer. However, I came back and plugged it into mine and I get the formatting requirement notification mentioned above. Ever since then I have not been able to use ANY mass storage decides on my computer. I could see how this could effect the Sandisk device, but why everything else? Can anyone offer the reason and hopefully a solution for this? Thanks again!