MP3's won't play, no sound on YouTube

I checked the sounds section on the control panel, and the speakers work. However, there's no sound on winamp, windows media player, and no sound on YouTube. Restarted, shutdown and rebooted, installed latest updates, but still no sound. Winamp plays the mp3, but no sound. Using e-machines model # EL 1200 with Vista Home Basic. Sound, when working, gets distorted and there's acoustic shifts in locations, pitch, and depth. Checked with both browsers, and same problem.
 
I'd try reinstalling the sound drivers but first uninstall them by first looking in Add/Remove Programs and uninstall the audio drivers you'll probably find listed in there
 
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