Ok... I just rebuilt my computer with a new M4A89GDT-Pro motherboard, a new AMD Phenom(tm) II X2 processor, a new GeForce GTS450 graphics card and new RAM... Everything seemed to be working fine at first, in fact Im using it right now... I started noticing problems when booting up my external drives. The computer didn't always recognize them, then the mouse would stop working, and on occasion the keyboard. I do a lot of Audio editing (radio programs and such), so I have a Mini-disk player on the side that I feed programs into my computer, via a Soundblaster that connects with a USB. All the drivers have been installed and no matter what I do, I am unable to get it to recognize the soundblaster, I did it once, and the computer sounds as if it found it, I even see the soundblaster in Sounds and Audio Devices, but no connection. I also am unable to feed in video via my fire-wire using the on-board port. Adobe Premier doesn't see it, I dont even get a noise saying it found something. I recently picked up a portable TB harddrive, my computer wont recognize it either. Even simple things like thumbdrives, I'll have unexpected crashes where the whole computer will either freeze or reboot the instant I insert a thumbdrive. Now I know the ports work sometimes, I have two externals fired up right now, no problems, except I cant switch them on until after the computer has made it to the desktop, otherwise it wont recognize it if I restart, I have to shut them off and switch them back on. Any ideas, I'm running behind on work and I need to get this solved... :blackeye: I'm fresh out of ideas. PLEASE HELP!!!