My computer has been under attack for a few days now. I have attached my latest HJT log. I don't have any spyware removal tools installed because I was unsure of which to use. Any help would be greatly appreciated. I was also wondering if whatever virus is causing the pop ups could possibly affect my usb hubs? Thank you in advance.

checking log file

Right Click on MyComputer icon and go to properties
Turn Off system restore
open IE and go to TOOLS OPTIONS delete temporary internet files and cookies
do a disk cleanup in your Start/accessories/system tools/ Menu

Download VUNDOand save it to your desktop

Double-click VundoFix.exe to run it.
Click the Scan for Vundo button.
Once it's done scanning, click the Remove Vundo button.
You will receive a prompt asking if you want to remove the files,
click YES
Once you click yes, your desktop will go blank as it starts removing
Vundo.
When completed, it will prompt that it will reboot your computer,
Click ok

After the reboot
download malwarebytes www.malwarebytes.org and install
run hijackthis and malwarebytes at the same time
select any files and or keys matching the attachment I posted in hyjackthis
but on both maiwarebytes and hijackthis click fix at the same time.then reboot immediatly.
if you forget to turn off system restore it will return no matter

reboot once complete, run hijack this and post your log here again

I'm going to try it right now, thank you so much!

I followed your instructions step by step. Here is the HJT log