I lurked on the thread below and followed all steps with some success, but avast still gets turned off on reboot. http://www.techspot.com/vb/topic149559.html Please review my info below and recommend next steps. thanks, allan Compaq Presario with XP Home SP3 installed History: 1. Grandma's computer, with expired antivirus for over a year allowed major infestation. 2. Reinstalled XP home and upgraded to SP3 on new partition C but unfortunately left D partition presario_RP alone. 3. Reinstalled Avast from scratch, but on reboots, get turned off. scan is clean and boot-time scan found nothing. 4. Ran malwarebytes and found nothing 5. Ran Rkill.com/exe/scr and found nothing 6. Ran exehelper with no results 7. Ran combofix with the results noted below. I noticed the autorun.inf deletion and thought I found the culprit, but still have the problem. 8. Ran eset NOD32 and found nothing. 9. Installed zonealarm to monitor things until we get to the bottom of this. Suggestions?