Next week you'll have a new virus or some such, drink quick!
Now keep yourself clean:
Good up to date antivirus
Hardware or software firewall
Install Microsoft Antispyware Beta
Run ad-aware and spybot twice a week
Use Firefox for Internet surfing
NEVER click a popup or ad no matter what!
Password protect your administrator user accounts
Turn off remote desktop support and remote assistance
Turn on automatic updates for Windows
Don't download any programs without checking on
http://www.spywareguide.com/
Use Spybot to Immunize you
Nevery try to find free cursors and/or free screensavers
Keep your tools (HJT, BHO Captor, CWShredder etc) up to date
And the list goes on.
cheers