It may work with 22a. I'm not sure. My system is a nforce4 ultra(simlar to nforce sli, but 1 pci-e connector instead of two), and I have 1 6600gt. I'm running it on a 350w antec psu with 21a on 12v. But a dual graphics card would take more power. Hopefully Tagan updated their psu's and gave them more power, which is very possible. Good luck.