Along with the usual weekly sales, the folks behind The Humble Bundle are offering mega savings on Frozen Synapse and six other indie titles (Trauma was added today). If you're looking for more mainline discounts, Steam has knocked 50% off the recently released Dungeon Siege III, Impulse cuts 50% off Dead Rising 2, Resident Evil 5, Street Fighter IV and others, Microsoft has reduced Assassin's Creed: Brotherhood to $19.99, while GamersGate has 60% off various dated hits including F.E.A.R., S.T.A.L.K.E.R. and Unreal.

Steam
67 Dungeon Siege III $24.99 (50% off)
73  Blood Bowl Legendary Edition $8.00 (80% off)
90  The Witcher 2: Assassins of Kings $29.99 (25% off)
79  Transformers: War for Cybertron $7.50 (75% off)
60  Sniper: Ghost Warrior $17.99 (40% off)
50  Post Apocalyptic Mayhem $4.99 (50% off)
48  Making History II: The War of the World $14.99 (50% off)
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Impulse
Dead Rising 2 $14.99 (50% off)
Resident Evil 5 $9.99 (50% off)
Devil May Cry 4 $9.99 (50% off)
Street Fighter IV $9.99 (50% off)
Lost Planet 2 $14.99 (50% off)
Dark Void $4.99 (50% off)
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GamersGate
Stellar Impact: The Tactical Space Game $13.37 (33% off)
Prince of Persia (Mac) $3.98 (60% off)
Prince of Persia: Two Thrones (Mac) $3.98 (60% off)
F.E.A.R. First Encounter Assault Recon $3.98 (60% off)
F.E.A.R. 2: Project Origin $3.98 (60% off)
S.T.A.L.K.E.R. Call of Pripyat $7.48 (50% off)
Unreal Complete Pack $23.18 (60% off)
Call of Juarez $8.00 (60% off)
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Direct2Drive
Medal of Honor $4.95 (75% off)
Battlefield: Bad Company 2 Vietnam $3.75 (75% off)
Dragon Age: Origins Ultimate Edition $7.50 (75% off)
Need for Speed Hot Pursuit $7.50 (75% off)
FIFA Manager 11 $9.95 (75% off)
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Games for Windows
Assassin's Creed: Brotherhood $19.99 (50% off)

Origin
Dead Space 2 $15.99 (20% off)
Bulletstorm $15.99 (20% off)

Good Old Games
50% off all Rebellion titles