This morning we had a problem with Internet Explorer being falsely spotted as malware/generic-S by Sophos. This was sorted out with an update not long after but not before alot of users called our helpdesk. Its not too common but does occasionally happen.
Avast eventually started taking days to scan idk if it was infected but I switched to avira and iv been happy ever since the end.
p.s. false positives happen no ones perfect, I just wish they would take wolf team off their lists, maybe they have by now i have not played in over a year but when I did I had to turn off avira, avast or avg in the past. I even wrote them emails.