Yeah for me it was the lack of DOS and reliance on system restore that caused the biggest issues. Once it went sideways (usually because the registry had corrupted for “reasons”) then it was hard if not impossible to recover the system and system restore did not save a system that could only boot to blue screen in my experience. It was the last non-NT kernel version of windows and it was a joy to move to windows 2000 then do where the registry didn’t seem as fragile.I am. I only had 9 PCs in my firm at the time, and the disasters of things like system restore was untouched. The biggest problem as I saw it was people trying to use ancient software with ME, even though MS made it clear that support for DOS mode was gone.
I had no love for ME, but in my opinion its biggest defect was the loose screws sitting in front of the monitor.
I also have a friend irl who says they had no problems with ME. So there we go.