The real question is "Just what are you trying to remove and/or update from your devices? And what type of symptoms/problem do you have?"
If, for example, you go to Device Manager, "Uninstall" a driver, then reboot, and it seems the driver reappears and just reinstalls itself
=> Start by first looking in Control Panel->Add/Remove Program
=> Is there an entry associated with the device or device manufacturer (e.g. if you want to remove your sound card is there an Add/Remove Program entry for Soundmax or Relatek or.. etc.?)
If you're trying to update a device, what device is it?