You don't have any (visible) spyware AFAIK.
But to be sure, do as Howard said and go to my post here first, and follow the instructions EXACTLY.
How to remove Begin2Search/Coolwebsearch and Other Nasties
When done, reboot in Safe Mode.
Run Hijackthis ON ITS OWN and let it 'fix':
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL =
http://us9.hpwis.com/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL =
http://srch-us9.hpwis.com/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Bar =
http://srch-us9.hpwis.com/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page =
http://srch-us9.hpwis.com/
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page =
http://us9.hpwis.com/
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = localhost
R3 - Default URLSearchHook is missing
O2 - BHO: PCTools Site Guard - {5C8B2A36-3DB1-42A4-A3CB-D426709BBFEB} - C:\PROGRA~1\SPYWAR~1\tools\iesdsg.dll (file missing)
O9 - Extra button: eBay - Homepage - {EF79EAC5-3452-4E02-B8BD-BA4C89F1AC7A} - C:\Program Files\IrfanView\Ebay\Ebay.htm (file missing)
O23 - Service: ZESOFT - Unknown - C:\WINDOWS\zeta.exe (file missing)