System runs at 100% all the time, low disk space

I have low disk space available even after I have uninstalled all the programs I don't use, also it is always running at 100 %. How do I solve issues?
 
DL WinDIrStat and delete all unnecessary files.

Run ATF or TFC or CCleaner to get rid of the temps

Still running out of space, flush your restore points.

Let's look at your startup.

On CCleaner goto Tools | Startup | Save to text file then post the resulting log.

When was the last time you cleaned your registry?

Please provide info on PC's specs
 
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