Struggling with spyware problems (at.exe, winsupdater.exe) unable to open taskmanager

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Hey,
Over the last day or two my computer has slowed almost to a halt due to spyware. I've been using Symantec Anti Virus but scans are making almost no progress (70 files scanned in 3 hours +) and I haven't been able to get any results from Microsoft AntiSpyware.

I can't open taskmanager.exe to stop the offending processes so I'm stuck there. Whevener I attempt to shut down I have to wait for 'winsupdater.exe' to stop running, and I've noticed a file called 'at.exe' in my C Drive Folder that reappears every time I delete it.

A HijackThis log has been attached, any help would be much appreciated :) .
 

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