On the topic of coil whine, I have no idea on that area too much because I have heard mixed reviews. Their are reports that the reference 7990's at least a few tend to have coil whine, but then I hear people say theirs do not whine so im honestly perplexed at times. There are videos on YouTube showing some doing the whine, and then their are some showing no whining so I just shake my head wondering.
As for stutter, that is still a debatable matter that will lead you down a fight from many perspectives. I am on the side that says its not as big a deal as many people make it out to be an its unnoticeable. I will direct you to a few reviews on this site for more information as they can put in perspective the supposed frame-stuttering issue many people put as the end all for cards.
GTX 780 Review (Games Sections
That should give you a good perspective, now bear in mind that's also on the older drivers (13.5 Beta 2) before the 13.8 Beta drivers came out even addressing the 'issue'.
The differences can be miniscule unless you go into low end multi-GPU setups which your not even looking at. But overall, the difference is miniscule and from what I read, it seems to be based on who is doing the reviews at times and what programs are being used.
Like I've said before, I run a quad-CFX setup using 2 HD 6990s, so I should be ripe for this problem, and honestly before that I had 2 GTX 580's (the PNY LC editions) and the difference besides an increase in FPS in multi-monitor setups has been nothing to say the least. I started around catalyst 12.4 or somewhere around there (I cant remember off the top of my head) and I have not seen some horrible stuttering or anything to say the least while even running in 5760x1080p resolution on Ultra.
Take what I said as just another persons opinion here, but honestly I don't see any of the game breaking horrible stuttering problems and from what I have read, I should be seeing this with my setup. 13.11Beta is what im on at the moment, and honestly, I have not had a crash since 13.4 (I had one crash with catalyst then, and 2 on 12.11) which was along time ago now and its been great.
My laptop has a GTX 675m and my spare desktop I made out of old parts that I bring to LAN party's for someone who has a machine who cant play games well (Or does not have one) has a pair of GTX 460 SE's inside (Friend gave me his old GTX 460 SE so I could SLI with my old one). Ive tested BF3 with both machines on a 1080p monitor just for fun before and they acted about the same on high settings (On ultra the 460 se setup starts to lose FPS). Don't count this as a legit review btw, just an opinion.
So that's my opinion on the matter, I hope this at least helps a little. Im not claiming to be an expert at everything computer related, but I feel some people exaggerate things that are not true for their fanboyish rage and it just annoys me.
If you want to avoid any chance of stutter and your still worried, grab one of the single GPU solutions (290X or 780) over the titan any day because the titan is just going to feel like a waste of money IMHO. A 780 is plenty and can easily overclock (You can buy models that are overclocked to Titan Levels) and having 6gb GDDR5 on one GPU is not beneficial to justify paying 300 bucks more.
Again, this is all an opinion (Except the review link), so I hope this helps!
Sorry its a bit long a post, oops