do the math
"Supports 48-bit addressing for large hard drives"
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How big can you go?
48-bit addressing, Equals = 144 petabytes (144,000,000 gigabytes).
As you can see that's WAYYYYYYY bigger than any hard drive on the market today. 144,000,000 gigabytes, so you should have no problem with a 500 gigabyte.
"48-bit Logical Block Addressing (LBA)is a technology which extends the capacity of IDE ATA/ATAPI devices beyond a previous limit of 137.4 GB. This limit applies to IDE ATA/ATAPI devices only and not to SCSI interface devices. The original design specification for the ATA interface only provided 28-bits with which to address the devices. This meant that a hard disk could only have a maximum of 268,435,456 sectors of 512 bytes of data thus limiting the ATA interface to a maximum of 137.4 gigabytes. With 48-bit addressing the limit is 144 petabytes (144,000,000 gigabytes)."