Solved Software found trojans, but said it couldn't find to delete. Ran 5 step

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The only thing I notice is that when I first turn on the computer-the startup music is garbled now everytime and the mouse is jumpy and hard to get on the box for entering my password. After the computer starts--everything seems to run smoothly though. But it takes awhile to finish loading up. Seems slow.
The Combofix /Uninstall didn't work for some reason so I used the IE -programs search -and deleted everything there with the name Combofix attached to it. Then the icon dissappeared.
Avast wouldn't let me run the OTC either. It kept asking me to run it in the sandbox so I added the program to the sandbox list, but nothing happened and I was never asked to run the clean up. I turned off the Avast and let OTC do it's thing. It ran for a few minutes and asked me to reboot the computer. I sure hope that was a SAFE site Not sure it ever went online to run anyway!!The avast was on when I downloaded the program and saved it to my desktop.
I'm hesitant to do a system restore until you tell me.
 
OTC is very safe. I wouldn't have given it to you if it wasn't. Please go ahead with the System Restore.

Slow loading can be an indication of having too many processes starting on boot. And usually you will also experience a slow shutdown. Only the following need to be checked on the Startup menu:
Antivirus
Firewall if using a 3rd party firewall
Touchpad process if on a laptop
Network processes if using Citrix/Pure Magic
Nothing else, including the printer

1. Call up a programs to use it from All Programs
2. When you want to Print, click on File> Print in the browser. You can do anything available in the printer from this screen.
3. Don't use auto-updating except for the AV. I see everyone running the Java updater (jusched) but have 5 or 6 outdated versions on the computer.
Auto-updates contact the internet several times daily-every day- looking for an update that may come in a month or 6 months.
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To remove entries from the Startup Menu using the msconfig utility:
  • Click on Start> Run> type in msconfig> enter>
    msconfig_open_xp.gif
  • Click on Selective Startup
  • Choose the Startup tab:
    startup_tab_xp.gif

    All images courtesy NetSquirrel
  • To expand the Command Column, (this shows what the process 'belongs' to) hold left mouse button down on the dividing line on frame above Location and move to the right to expand.
  • Uncheck any processes you do not need to start on boot.
  • Click on Apply> OK when finished.
NOTE:
When you reboot the system the first time after making changes using the msconfig utility, a nag message comes up that can be ignored and closed after checking 'don't show this message again.' Remain in Selective Startup to retain those changes.

Make friends with your computer, but you be the boss- don't let it run you!
 
Ok...all done. I'm the boss of this baby NOW! You are a wonderful person. I would like to do something nice for you ...besides get out off your wall. Do you accept gifts? Have a wonderful evening. I'll let you know in a few days if everything is still working well.
 
It was my pleasure to help you. The nicest thing you can do for me and the best gift I'd like is for you to remember the things we did and the things we went over. Some of those things are very basic and can be of help to you in the future.
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All of the following may not be compatible with all versions of Windows or all browsers. They are suggestion only.

You may find the following helpful: (Links are Bold Blue)
Tips for added security and safer browsing:
  1. Browser Security
    [o][url="http://www.bleepingcomputer.com/tutorials/tutorial102.htm]Make Internet Explorer safer][/url]
    [o] Use a Site Advisor..
    Have layered Security:
  2. Antivirus Software(only one):
    [o] Comodo AV
    [o]Avast Free
    [o]Microsoft Security Essentials
  3. Firewall (only one)
    [o] Zone Alarm Free
    [o]Comodo Firewall Free
  4. Antispyware/Security: I recommend all of the following:
    [o]Spywareblaster:Protects against bad ActiveX.
    [o]IE/Spyad Restricts bad domains.
    [o]MVPS Hosts files Directs HOSTS file to 127.0.0.1 which is your local computer.
  5. Stay current on updates:
    [o] Windows Updates. You should get All updates marked Critical and the current SP updates.
    [o] Adobe Reade. Uninstall old.
    [o]Java Uninstall old.
  6. Reset Cookies to prevent Tracking Cookies:
    [o]For Internet Explorer: Internet Options (through Tools or Control Panel) Privacy tab> Advanced button> check 'override automatic Cookie handling'> check 'accept first party Cookies'> check 'Block third party Cookies'> check 'allow per session Cookies'> Apply> OK.
    [o]For Firefox: Tools> Options> Privacy> Cookies> check ‘accept Cookies from Sites’> Uncheck 'accept third party Cookies'> Set Keep until 'they expire'. This will allow you to keep Cookies for registered sites and prevent or remove others. (Note: for Firefox v3.5, after Privacy click on 'use custom settings for History.')
    I suggest using the following two add-on for Firefox. They will prevent the Tracking Cookies that come from ads and banners and other sources:
    AdBlock Plus
    Easy List
  7. Do regular Maintenance
    [o]To include Disc Cleanup, Defrag, Error Check/
  8. Remove Temporary Internet Files regularly:
    [o]TFC
  9. System Restore GuideUnderstand Restore Points> why you need to clean and set restore points and what information is in them.
    [*] Practice Safe Email Handling
    [o] Don't open email from anyone you don't know.
    [o] Don't open Attachments in the email. Save to your desktop and scan for viruses using a right click
    [o] Don't leave your personal email address on the internet/ Have a separate email account on free web-based mail.

Please let me know if you find any bad links.
 
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