Identify the make of your hard drive and then use one of the links below to get the manufacturers diagnostic for ISO CD. Burn the image file to a CD, boot the PC with the disc in the drive and run the diagnostics. You first need to set the CD drive to 1st in the boot order in the Bios setup.
If you do not have an image burner use this free software to make the CD.
http://www.isoimageburner.com/
ExcelStor: http://www.excelstor.com/eng/support.php?sub_id=3
Hitachi/IBM: http://www.hitachigst.com/support/downloads/
Samsung: http://www.samsung.com/global/business/hdd/support/downloads/support_in_es.html
Seagate, Maxtor & Quantum:http://www.seagate.com/www/en-us/support/downloads
Western Digital:http://support.wdc.com/product/download.asp?lang=en
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Toshiba Fujitsu: http://sdd.toshiba.com/main.aspx?Path=SoftwareUtilities#diagnostic
If you have a Toshiba hard drive I would suggest the use of the diagnostics from the Seagate link as this will work on all makes of drive and on any OS.
It is perfectly fine to run SuperAntiSpyware, Malwarebytes, and MSE in conjunction with one another
1. Press Start > type cmd in the search box. A box will open with CMD at the top, right click on it and select run as administrator. Another box will open, at the prompt, type chkdsk /r and press enter. (Note the gap between the k and the /)
2.Check disk will start to run but then it will say:
Chkdsk cannot run because the volume is in use by another process. Would you like to schedule this volume to be checked the next time the system restarts? (Y/N) Type Y for yes, and press enter. Then reboot the computer into normal mode. Chkdsk will start when Windows begins loading again. Let all 5 phases run and don't use or turn off the computer. (The chkdsk process may take an hour or more to finish.)
3.Chkdsk finds any corrupted files and fixes them. Read the results of each phase as it finishes. During the final phase, it will notify you if it finds any corrupted files. It will also report on finding any bad sectors on the hard drive, these will be blocked from further use and the data on them moved.
4.When the Check Disk is done, it will finish loading Windows.
Let us know what happens.