I seriously doubt if you have compatibility issues if you are going from a current SSD to a larger one. Only thing I can forsee is if you have a system that has only supports SATAII & you get a SSD that is SATAIII - you will be losing performance, but it should work. Post your system specs, that will help immensely in answering your compatibility questions. try speccy: http://www.piriform.com/speccy to grab all your system specs & post them back. Hope this helps, take care!