Loud continuous beep at start up

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we have a Toshiba satellite computer with vista. when we start the computer, before it gets to the microsoft startup we get a loud continuous beep. if we use the F8 key we get by this problem and the computer starts and runs but we get a chatter where the "3" key keeps repeating and/or the cursor drops to the last item on any drop-down? Any idea what this is?
 
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