If your board will indeed handle 4GB of RAM across the 2 slots, you should be able to install a 2GB module in slot 2. This will cause either of 2 things.
1. your RAM will run in dual channel mode for 1GB of each slot, and the top half of the 2GB stick will run in single channel,
Or 2. The RAM will run in single channel, period.
If you put one 2GB stick in slot one, the RAM will be single channel.
For either event to happen, the RAM must be generic, not dissimilar high performance / standard (generic), modules.
Keep in mind that 32 bit XP doesn't do well with more than 2GB RAM total. (You didn't post your OS).
Asustek boards, (at one time), were picky about the RAM they would accept. I really don't know about your particular model.
DDR-2 has become a "replacement part". That's the reason the price is high compared to DDR-3. Just be thankful you don't have DDR.
Ouch because the shop that I bought has 1GB but no 2b and another has 2GB and 4gb but ddr3..
What kind of memory issues will I get of that?
If you have to ask whether DDR-2 or DDR-3 are compatible, (they aren't), I'm no so sure you should be fumbling around inside your computer.