Windows\system32\ntdll.dll is open error when installing Windows XP SP3

I need help, I cant install windows xp sp3 on my computer
I get this error message

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Service Pack 3 Setup Error
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The file c:\windows\system32\ntdll.dll is open or in use by another application.

Close all other applications and then click Retry.
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Retry Cancel
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I get this message everytime I try to install. I have already disabled my antivirus and antimalware but still this error shows up. Help please.

------Malwarebytes Anti-Malware (PRO) 1.75.0.1300-------
www.malwarebytes.org

Database version: v2013.10.02.06

Windows XP Service Pack 2 x86 NTFS
Internet Explorer 6.0.2900.2180
MOON :: MOON-2F8500C917 [limited]

Protection: Disabled

10/2/2013 11:03:30 PM
mbam-log-2013-10-02 (23-03-30).txt

Scan type: Quick scan
Scan options enabled: Memory | Startup | Registry | File System | Heuristics/Extra | Heuristics/Shuriken | PUP | PUM
Scan options disabled: P2P
Objects scanned: 246681
Time elapsed: 13 minute(s), 54 second(s)

Memory Processes Detected: 0
(No malicious items detected)

Memory Modules Detected: 0
(No malicious items detected)

Registry Keys Detected: 0
(No malicious items detected)

Registry Values Detected: 0
(No malicious items detected)

Registry Data Items Detected: 0
(No malicious items detected)

Folders Detected: 0
(No malicious items detected)

Files Detected: 1
D:\Documents and Settings\MOON\My Documents\Downloads\SoftonicDownloader_for_picpick.exe (PUP.Optional.Softonic.A) -> Quarantined and deleted successfully.


(end)
 
You can not install on a running (ie already booted) system.

One choice is to run Windows Update from an admin login and let it perform Updates. If the SP3 is an update that is available, Update will do the right thing.

The other choice is to boot a CD and perform an install from the CD (ie the PC is not running from the HD).
 
I have already tried running Windows Update by clicking the yellow shield at the bottom right of the screen but it always fails to install service pack 3. I need help please. Thank you
 
In that case I'd suggest you go to our Malware and Virus removal forum. Look at the posts at top of the forum. One of them describes the steps to take in requesting help.

The experts there will take a deep look for malware
 
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