Depends on the Dell. Some of the Dell Optiplex and Dimension desktops had defective, or extremely high failure rates on optical drives, with the inability to read, or blue screens showing up after about 8 -10 months of use. So the problem may not be related to Norton. What is the model of your Dell with Service Tag? How old is it.
Replacing the drive can be done for $22 an a philips screwdriver.
Do you still bet the BIOS screen at startup when you depress <F12> See if the drive is detected in the BIOS. If you don't get that screen, then your problem may be more serious.