Multiple iexplore.exe instances and URL:Mal infection

Okay, I'm back after the creating the new restore point with OTL.
I noticed in the log for it that it talks about a User: matt
My user account is Fuzzy, and I don't intend to have any other user accounts.
Checking the list of accounts in Control Panel > User Accounts > Manage Another Account, I see Fuzzy, ASP.NET Machine Account and Guest, but Guest is listed as turned off. I see no mention there of matt and I've got no idea what the ASP.NET Machine Account is.
Is there anything there I should be concerned about?

Here's the OTL log:
All processes killed
========== OTL ==========
========== COMMANDS ==========

[EMPTYTEMP]

User: All Users

User: Default
->Temp folder emptied: 0 bytes
->Temporary Internet Files folder emptied: 0 bytes

User: Default User
->Temp folder emptied: 0 bytes
->Temporary Internet Files folder emptied: 0 bytes

User: Fuzzy
->Temp folder emptied: 43548 bytes
->Temporary Internet Files folder emptied: 87126 bytes
->Java cache emptied: 1880 bytes
->FireFox cache emptied: 0 bytes
->Google Chrome cache emptied: 83075296 bytes
->Flash cache emptied: 0 bytes

User: matt
->Temp folder emptied: 0 bytes

User: Public
->Temp folder emptied: 0 bytes

User: UpdatusUser
->Temp folder emptied: 0 bytes
->Temporary Internet Files folder emptied: 0 bytes

%systemdrive% .tmp files removed: 0 bytes
%systemroot% .tmp files removed: 0 bytes
%systemroot%\System32 .tmp files removed: 0 bytes
%systemroot%\System32 (64bit) .tmp files removed: 0 bytes
%systemroot%\System32\drivers .tmp files removed: 0 bytes
Windows Temp folder emptied: 6586 bytes
%systemroot%\sysnative\config\systemprofile\AppData\Local\Microsoft\Windows\Temporary Internet Files folder emptied: 33170 bytes
RecycleBin emptied: 0 bytes

Total Files Cleaned = 79.00 mb


[EMPTYFLASH]

User: All Users

User: Default

User: Default User

User: Fuzzy
->Flash cache emptied: 0 bytes

User: matt

User: Public

User: UpdatusUser

Total Flash Files Cleaned = 0.00 mb


[EMPTYJAVA]

User: All Users

User: Default

User: Default User

User: Fuzzy
->Java cache emptied: 0 bytes

User: matt

User: Public

User: UpdatusUser

Total Java Files Cleaned = 0.00 mb

Restore point Set: OTL Restore Point

OTL by OldTimer - Version 3.2.69.0 log created on 01092013_090220

Files\Folders moved on Reboot...
C:\Users\Fuzzy\AppData\Local\Temp\FXSAPIDebugLogFile.txt moved successfully.
File move failed. C:\Windows\temp\_avast_\Webshlock.txt scheduled to be moved on reboot.

PendingFileRenameOperations files...

Registry entries deleted on Reboot...

Okay, all done!
I scrapped Adobe Reader and installed Foxit instead.
I've got WOT and Secunia PSI installed now, got TFC and MBAM ready to run weekly.
Qualys Browser Check tells me I have Internet Explorer 8, which it lists as an insecure version. I have no interest in ever using Internet Explorer, so I'd prefer to remove it completely if possible rather than wasting bandwidth downloading new versions of it.
Is it possible to remove IE these days or is it tightly welded into the OS?

Okay, thanks for all your help!