No, I doubt that it ever would... never have seen that be a problem it in our many years of working on these monsters.
I would suspect, without knowing your system and setup, an old drive, a worn out dirve, a cheap drive such as Maxtor or Hitachi or TriGem or MDT, an infestation, or a badly corrupted or damaged Windows file system, or a drive that has less than 18 percent free space, or a new Seagate or Western Digital 1 TB, 1.5 terrabyte, or 2 terrabyte drive empty or full...
But a defective CMOS battery can cause a drive to become corrupted, which can then be the problem.