Skype Voice Call issues even with High Speed Internet

Hey!
I hope someone could provide a little advice about router configuration. I am running Skype for Business on my laptop. It works perfectly at my office on WIFi, but not so well while I am at home. This make me suspicious of my Router (Asus RT-N66U) which works extremely well otherwise without any issues with signal or anything.
I guess the issue is with settings of the router. I am not very sure about what changes are required on what settings to optimize the VoIP through the router. Can someone help me with optimizing the settings?
 
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